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tisztességtelen Csarnok smink overall mutation load and p53 mutations Lehalkít orr Mókus

Acetylation halts missense mutant p53 aggregation and rescues tumor  suppression in non-small cell lung cancers - ScienceDirect
Acetylation halts missense mutant p53 aggregation and rescues tumor suppression in non-small cell lung cancers - ScienceDirect

p53 Is the Most Frequently Mutated Gene in Cancer, but Can We Target It?
p53 Is the Most Frequently Mutated Gene in Cancer, but Can We Target It?

Prognostic value of TP53 mutation location in breast cancer | CMAR
Prognostic value of TP53 mutation location in breast cancer | CMAR

TP53 mutational landscape of metastatic head and neck cancer reveals  patterns of mutation selection - eBioMedicine
TP53 mutational landscape of metastatic head and neck cancer reveals patterns of mutation selection - eBioMedicine

Implications of driver genes associated with a high tumor mutation burden  identified using next‑generation sequencing on immunotherapy in  hepatocellular carcinoma
Implications of driver genes associated with a high tumor mutation burden identified using next‑generation sequencing on immunotherapy in hepatocellular carcinoma

Mutational processes shape the landscape of TP53 mutations in human cancer  | Nature Genetics
Mutational processes shape the landscape of TP53 mutations in human cancer | Nature Genetics

Frequency of p53 mutations in human cancers. (A) Schematic picture... |  Download Scientific Diagram
Frequency of p53 mutations in human cancers. (A) Schematic picture... | Download Scientific Diagram

Overall survival curves of patients with p53 mutation results. (A) p53... |  Download Scientific Diagram
Overall survival curves of patients with p53 mutation results. (A) p53... | Download Scientific Diagram

IJMS | Free Full-Text | Do Mutations Turn p53 into an Oncogene?
IJMS | Free Full-Text | Do Mutations Turn p53 into an Oncogene?

Mutant p53 elicits context-dependent pro-tumorigenic phenotypes | Oncogene
Mutant p53 elicits context-dependent pro-tumorigenic phenotypes | Oncogene

Mutant p53 achieved Gain-of-Function by promoting tumor growth and immune  escape through PHLPP2/AKT/PD-L1 pathway
Mutant p53 achieved Gain-of-Function by promoting tumor growth and immune escape through PHLPP2/AKT/PD-L1 pathway

Mutant p53 Gain of Function in Two Mouse Models of Li-Fraumeni Syndrome:  Cell
Mutant p53 Gain of Function in Two Mouse Models of Li-Fraumeni Syndrome: Cell

TP53 exon-6 truncating mutations produce separation of function isoforms  with pro-tumorigenic functions | eLife
TP53 exon-6 truncating mutations produce separation of function isoforms with pro-tumorigenic functions | eLife

Gain of function in somatic TP53 mutations is associated with immune‐rich  breast tumors and changes in tumor‐associated macrophages - Behring - 2019  - Molecular Genetics & Genomic Medicine - Wiley Online Library
Gain of function in somatic TP53 mutations is associated with immune‐rich breast tumors and changes in tumor‐associated macrophages - Behring - 2019 - Molecular Genetics & Genomic Medicine - Wiley Online Library

LRP1B or TP53 mutations are associated with higher tumor mutational burden  and worse survival in hepatocellular carcinoma
LRP1B or TP53 mutations are associated with higher tumor mutational burden and worse survival in hepatocellular carcinoma

Germline TP53 mutations undergo copy number gain years prior to tumor  diagnosis | Nature Communications
Germline TP53 mutations undergo copy number gain years prior to tumor diagnosis | Nature Communications

Evaluating the prognostic significance of p53 and TP53 mutations in  HPV-negative hypopharyngeal carcinoma patients: a 5-year follow-up  retrospective study | BMC Cancer | Full Text
Evaluating the prognostic significance of p53 and TP53 mutations in HPV-negative hypopharyngeal carcinoma patients: a 5-year follow-up retrospective study | BMC Cancer | Full Text

Targeting a neoantigen derived from a common TP53 mutation | Science
Targeting a neoantigen derived from a common TP53 mutation | Science

Low-burden TP53 mutations in CLL: clinical impact and clonal evolution  within the context of different treatment options - ScienceDirect
Low-burden TP53 mutations in CLL: clinical impact and clonal evolution within the context of different treatment options - ScienceDirect

Diverse rescue potencies of p53 mutations to ATO are predetermined by  intrinsic mutational properties | Science Translational Medicine
Diverse rescue potencies of p53 mutations to ATO are predetermined by intrinsic mutational properties | Science Translational Medicine

Evaluating the prognostic significance of p53 and TP53 mutations in  HPV-negative hypopharyngeal carcinoma patients: a 5-year follow-up  retrospective study | BMC Cancer | Full Text
Evaluating the prognostic significance of p53 and TP53 mutations in HPV-negative hypopharyngeal carcinoma patients: a 5-year follow-up retrospective study | BMC Cancer | Full Text

Analysis of P53 mutations and their expression in 56 colorectal cancer cell  lines | PNAS
Analysis of P53 mutations and their expression in 56 colorectal cancer cell lines | PNAS

Mutations of the p53 Gene as a Prognostic Factor in Aggressive B-Cell  Lymphoma | NEJM
Mutations of the p53 Gene as a Prognostic Factor in Aggressive B-Cell Lymphoma | NEJM

TP53 mutation spectrum in primary colorectal cancers. a Proportion of... |  Download Scientific Diagram
TP53 mutation spectrum in primary colorectal cancers. a Proportion of... | Download Scientific Diagram